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Kallikrein 6 抗体 (C-Term)

This anti-Kallikrein 6 antibody is a 兔 多克隆 antibody detecting Kallikrein 6 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN6257305
发货至: 中国

Quick Overview for Kallikrein 6 抗体 (C-Term) (ABIN6257305)

抗原

See all Kallikrein 6 (KLK6) 抗体
Kallikrein 6 (KLK6)

适用

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宿主

  • 67
  • 7
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克隆类型

  • 69
  • 7
多克隆

标记

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This Kallikrein 6 antibody is un-conjugated

应用范围

  • 61
  • 33
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 7
    • 5
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    • 1
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    C-Term

    特异性

    KLK6 Antibody detects endogenous levels of total KLK6.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human KLK6, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    Kallikrein 6 (KLK6)

    别名

    KLK6

    背景

    Description: Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

    Gene: KLK6

    分子量

    30 kDa

    基因ID

    5653

    UniProt

    Q92876

    途径

    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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