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Kallikrein 6 抗体 (N-Term)

The 兔 多克隆 anti-Kallikrein 6 antibody (ABIN2778179) specifically detects Kallikrein 6 in WB 和 IHC. The antibody is reactive with 人, 犬 和 马 samples.
产品编号 ABIN2778179
发货至: 中国
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Quick Overview for Kallikrein 6 抗体 (N-Term) (ABIN2778179)

抗原

See all Kallikrein 6 (KLK6) 抗体
Kallikrein 6 (KLK6)

适用

  • 80
  • 9
  • 4
  • 2
人, 犬, 马

宿主

  • 83
  • 5
  • 2
兔

克隆类型

  • 85
  • 5
多克隆

标记

  • 36
  • 11
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Kallikrein 6 antibody is un-conjugated

应用范围

  • 58
  • 28
  • 22
  • 22
  • 13
  • 13
  • 12
  • 10
  • 7
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 17
    • 17
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    KLK6 Antibody - N-terminal region

    序列

    KHNLRQRESS QEQSSVVRAV IHPDYDAASH DQDIMLLRLA RPAKLSELIQ

    预测反应

    Dog: 92%, Horse: 92%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against KLK6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human KLK6
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33888-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Kallikrein 6 (KLK6)

    别名

    KLK6

    背景

    Background Information: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.

    Gene Name: Kallikrein-related peptidase 6

    Alternative Symbols: hK6, Bssp, Klk7, SP59, PRSS9, PRSS18

    Protein Name: Kallikrein-6

    分子量

    25kDa

    基因ID

    5653

    NCBI登录号

    NP_001012982

    UniProt

    Q92876

    途径

    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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