ITPR1 抗体 (pSer1756, pSer1764)
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- 抗原 See all ITPR1 抗体
- ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
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抗原表位
- pSer1756, pSer1764
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ITPR1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Phospho-IP3 Receptor (Ser1756) Antibody detects endogenous levels of IP3 Receptor only when phosphorylated at Ser1756.
- 纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- 免疫原
- A synthesized peptide derived from RAT IP3 Receptor(P29994) around the phosphorylation site of Ser1756. This site is equivalent to Ser1764 in the human IP3 receptor sequence.
- 亚型
- IgG
- Top Product
- Discover our top product ITPR1 Primary Antibody
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anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) (AA 2411-2758) antibody
ITPR1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) antibodyITPR1 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) (AA 1707-1966) antibodyITPR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) (AA 2731-2749) antibodyITPR1 适用: 人, 小鼠, 大鼠, Cow IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) antibodyITPR1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) (AA 1892-1911) antibodyITPR1 适用: 人, 小鼠, 大鼠, Cow, 猴 IHC, WB, IP, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) (pSer1764) antibodyITPR1 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) (AA 2470-2577) antibodyITPR1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) antibodyITPR1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1) antibodyITPR1 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
- 别名
- ITPR1 (ITPR1 产品)
- 别名
- D6Pas2 antibody, ENSMUSG00000072853 antibody, Gm10429 antibody, IP3R1 antibody, InsP3R antibody, Ip3r antibody, Itpr-1 antibody, P400 antibody, Pcp-1 antibody, Pcp1 antibody, opt antibody, I145TR antibody, InsP3R1 antibody, INSP3R1 antibody, IP3R antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, inositol 1,4,5-trisphosphate receptor type 1 antibody, inositol 1,4,5-trisphosphate receptor 1 antibody, inositol 1,4,5-trisphosphate receptor, type 1 antibody, ITPR1 antibody, Itpr1 antibody
- 背景
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Description: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
Gene: ITPR1
- 分子量
- 314kDa
- 基因ID
- 3708
- UniProt
- Q14643
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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