TNF alpha 抗体
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北京 101111
Quick Overview for TNF alpha 抗体 (ABIN6254207)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- anti-TNF alpha
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序列
- MSTESMIRDV ELAEEALPKK TGGPQGSRRC LFLSLFSFLI VAGATTLFCL LHFGVIGPQR EEFPRDLSLI SPLAQAVRSS SRTPSDKPVA HVVANPQAEG QLQWLNRRAN ALLANGVELR DNQLVVPSEG LYLIYSQVLF KGQGCPSTHV LLTHTISRIA VSYQTKVNLL SAIKSPCQRE TPEGAEAKPW YEPIYLGGVF QLEKGDRLSA EINRPDYLDF AESGQVYFGI IAL
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特异性
- Detects a band of approximately 17 kDa using Raw264.7 cell line by Western blot.
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产品特性
- Tumor necrosis factor
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纯化方法
- Epitope affinity purified
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免疫原
- Purified recombinant human TNF-_ produced in E. coli.
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亚型
- IgG
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应用备注
- WB:1:500-1:2,000
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限制
- 仅限研究用
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缓冲液
- PBS, 20 % glycerol and 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody solution should be gently mixed before use.
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储存条件
- 4 °C,-20 °C
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储存方法
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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别名
- TNF alpha
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背景
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Goat polyclonal antibody to TNF alpha. TNF-α is produced by a variety of immune cells including NK cells, B cells, T cells and macrophages. It is multifunctional proinflammatory cytokine that belongs to the tumour necrosis factor (TNF) superfamily. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is involved in the regulation of several processes including lipid metabolism cell differentiation and proliferation, coagulation and apoptosis. It has been implicated in a variety of diseases, including cancer and autoimmune diseases.
APC1, cachectin, tumor necrosis factor ligand superfamily member 2, macrophage-derived TNF, TNF-a, TNF monocyte-derived, tumor necrosis factor-alpha antibody.
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
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