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Ataxin 3 抗体 (AA 120-250)

The 山羊 多克隆 anti-Ataxin 3 antibody is suitable to detect Ataxin 3 in samples from 人, 小鼠, 大鼠, Cow, 绵羊, 马, 兔, 豚鼠, 犬, 猴, Pig, Cat, 小鸡, 驴, 山羊, Hamster 和 Avian. It has been validated for WB.
产品编号 ABIN6254159
发货至: 中国
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Quick Overview for Ataxin 3 抗体 (AA 120-250) (ABIN6254159)

抗原

See all Ataxin 3 (ATXN3) 抗体
Ataxin 3 (ATXN3)

适用

人, 小鼠, 大鼠, Cow, 绵羊, 马, 兔, 豚鼠, 犬, 猴, Pig, Cat, 小鸡, 驴, 山羊, Hamster, Avian

宿主

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山羊

克隆类型

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多克隆

标记

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This Ataxin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 120-250

    原理

    Anti-ATXN3

    序列

    KEHWFTVRKL GKQWFNLNSL LTGPELISDT YLALFLAQLQ QEGYSIFVVK GDLPDCEADQ LLQMIRVQQM HRPKLIGEEL AQLKEQRVHK TDLERVLEAN DGSGMLDEDE EDLQRALALS RQEIDMEDEE ADL

    特异性

    Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB0089.

    产品特性

    Ataxin 3

    纯化方法

    Epitope affinity purified

    免疫原

    Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.

    亚型

    IgG
  • 应用备注

    WB:1:250-1:2,000

    限制

    仅限研究用
  • 缓冲液

    preservatives. Glycerol and azide FREE.

    储存液

    Azide free

    注意事项

    The antibody solution should be gently mixed before use.

    储存条件

    4 °C,-20 °C

    储存方法

    For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
  • 抗原

    Ataxin 3 (ATXN3)

    别名

    ATXN3

    背景

    Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.

    AT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein antibody.

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