Ataxin 3 抗体 (AA 120-250)
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北京 101111
Quick Overview for Ataxin 3 抗体 (AA 120-250) (ABIN6254159)
抗原
See all Ataxin 3 (ATXN3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-250
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原理
- Anti-ATXN3
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序列
- KEHWFTVRKL GKQWFNLNSL LTGPELISDT YLALFLAQLQ QEGYSIFVVK GDLPDCEADQ LLQMIRVQQM HRPKLIGEEL AQLKEQRVHK TDLERVLEAN DGSGMLDEDE EDLQRALALS RQEIDMEDEE ADL
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特异性
- Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB0089.
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产品特性
- Ataxin 3
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纯化方法
- Epitope affinity purified
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免疫原
- Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
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亚型
- IgG
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应用备注
- WB:1:250-1:2,000
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限制
- 仅限研究用
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缓冲液
- preservatives. Glycerol and azide FREE.
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储存液
- Azide free
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注意事项
- The antibody solution should be gently mixed before use.
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储存条件
- 4 °C,-20 °C
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储存方法
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- Ataxin 3 (ATXN3)
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别名
- ATXN3
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背景
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Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.
AT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein antibody.
抗原
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