SERPINA1 抗体
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- 抗原 See all SERPINA1 抗体
- SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SERPINA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Protein G affinity
- 免疫原
- A human partial recombinant protein was used as the immunogen for this Alpha 1 Antitrypsin antibody.
- 克隆位点
- AAT-1379
- 亚型
- IgG1
- Top Product
- Discover our top product SERPINA1 Primary Antibody
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anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 25-413) antibody
SERPINA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 23-237) antibodySERPINA1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5D1D2 unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 27-181) antibodySERPINA1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) antibodySERPINA1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 25-315) antibodySERPINA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 269-419) antibodySERPINA1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8C7A4 unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 211-411) antibodySERPINA1 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 165-444) antibodySERPINA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) antibodySERPINA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) (AA 1-418) antibodySERPINA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 0.5-1 μg/mL
IHC (Paraffin): 0.5-1 μg/mL
IF: 0.5-1 μg/mL
Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml
Titration of the Alpha 1 Antitrypsin antibody may be required due to differences in protocols and secondary/substrate sensitivity. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- 抗原
- SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))
- 别名
- Alpha 1 Antitrypsin (SERPINA1 产品)
- 别名
- AACT antibody, ACT antibody, GIG25 antibody, A1AT antibody, PI antibody, alpha-1-PI antibody, A1A antibody, AAT antibody, PI1 antibody, PRO2275 antibody, alpha1AT antibody, Pi antibody, Spi1 antibody, MGC64429 antibody, serpina1d antibody, Aps antibody, SERPINA3-5 antibody, serpin family A member 3 antibody, alpha-1-antiproteinase F precursor antibody, serpin family A member 1 antibody, alpha-1-antitrypsin antibody, calumenin antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, SH2B adaptor protein 2 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog antibody, SERPINA3 antibody, LOC100008973 antibody, SERPINA1 antibody, LOC100328621 antibody, CALU antibody, Serpina1 antibody, serpina1.S antibody, serpina1 antibody, SPIA5 antibody, Sh2b2 antibody, Calu antibody, serpina1.L antibody
- 背景
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Alpha-1 Antitrypsin or alpha1-antitrypsin (A1AT) is a protease inhibitor belonging to the serpin superfamily. It is generally known as serum trypsin inhibitor. Alpha 1-antitrypsin is also referred to as alpha-1 proteinase inhibitor (A1PI) because it inhibits a wide variety of proteases. It protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 1.5 - 3.5 gram/liter (in US the reference range is generally expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation. In its absence (such as in alpha 1-antitrypsin deficiency), neutrophil elastase is free to break down elastin, which contributes to the elasticity of the lungs, resulting in respiratory complications such as emphysema, or COPD (chronic obstructive pulmonary disease) in adults and cirrhosis in adults or children.
Like all serine protease inhibitors, A1AT has a characteristic secondary structure of beta sheets and alpha helices. Mutations in these areas can lead to non-functional proteins that can polymerise and accumulate in the liver (infantile hepatic cirrhosis). [Wiki]
- 基因ID
- 5265
- UniProt
- P01009
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