TGF-beta 抗体
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- 抗原 See all TGF-beta (TGFb) 抗体
- TGF-beta (TGFb)
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适用
- 人, 小鼠, 大鼠, Cow, 犬, Hamster, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TGF-beta antibody is un-conjugated
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应用范围
- Neutralization (Neut)
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- Bovine TGF-beta2 protein was used as the immunogen for the TGF-beta antibody.
- 克隆位点
- 1D11-16-8
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TGFb Primary Antibody
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- 应用备注
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Functional Activity: Cytokine Neutralization (Order SAF formulation)
Optimal dilution of the TGF-beta antibody should be determined by the researcher. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.2 mg/mL
- 缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- 抗原
- TGF-beta (TGFb)
- 别名
- TGF-beta (TGFb 产品)
- 别名
- CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor, beta 1 antibody, TGFB1 antibody, Tgfb1 antibody
- 背景
- This mAb recognizes TGF beta 1, 2 and 3. Three TGFbs have been identified in mammals. TGFb1, TGFb2 and TGFb3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFb requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFb3 protein has approximately 80 % identity to the mature region of both TGFb1 and TGFb2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGFb's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.
- 基因ID
- 7040, 7043, 7042
- UniProt
- P01137, P10600, P61812
- 途径
- EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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