SRRT 抗体 (AA 733-766)
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北京 101111
Quick Overview for SRRT 抗体 (AA 733-766) (ABIN6244193)
抗原
See all SRRT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 733-766
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 733-766 amino acids from DANRE srrt.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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别名
- srrt
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背景
- Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
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分子量
- 103274
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UniProt
- Q66I22
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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