This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This WDR51B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 386-417 amino acids from the C-terminal region of human WDR51B.
Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:< a href="http://www.uniprot.org/citations/20008567" target="_blank">20008567). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:< a href="http://www.uniprot.org/citations/19109428" target="_blank">19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation. Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:< a href="http://www.uniprot.org/citations/23015594" target="_blank">23015594). Required for retinal integrity (PubMed:< a href="http://www.uniprot.org/citations/25044745" target="_blank">25044745).