GSK3 beta 抗体 (N-Term)
(1 reference)Quick Overview for GSK3 beta 抗体 (N-Term) (ABIN6243417)
抗原
See all GSK3 beta (GSK3b) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 4-34, N-Term
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GSK3 beta (GSK3B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human GSK3 beta (GSK3B).
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亚型
- Ig Fraction
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anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibody
GSK3b 适用: 人, 小鼠 WB, IF, IP 宿主: 小鼠 Monoclonal 2E6-D6-C12 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (N-Term) antibodyGSK3b 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 30-59) antibodyGSK3b 适用: 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34) antibodyGSK3b 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33) antibodyGSK3b 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 362-395) antibodyGSK3b 适用: 大鼠 WB 宿主: 兔 Polyclonal RB56577 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33), (pSer9) antibodyGSK3b 适用: 人 WB 宿主: 兔 Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b 适用: 人, 小鼠, 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal 2E6-D6-C12 unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).
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: "Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma." in: IUBMB life, Vol. 66, Issue 7, pp. 507-18, (2014) (PubMed).
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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别名
- GSK3 beta (GSK3B)
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背景
- GSK3B, a member of the Ser/Thr protein kinase family, participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. The protein is inhibited when phosphorylated by AKT1 or ILK1. Expressed is detected in testis, thymus, prostate and ovary, and weakly in lung, brain and kidney.
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分子量
- 46744
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NCBI登录号
- NP_001139628, NP_002084
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UniProt
- P49841
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途径
- WNT signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
抗原
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