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RUNX2 抗体 (N-Term)

This anti-RUNX2 antibody is a 兔 多克隆 antibody detecting RUNX2 in IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6243280
发货至: 中国

Quick Overview for RUNX2 抗体 (N-Term) (ABIN6243280)

抗原

See all RUNX2 抗体
RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RUNX2 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB10543
  • 抗原表位

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    AA 1-30, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RUNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human RUNX2.

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ushijima, Okazaki, Tsushima, Iwamoto: "CCAAT/enhancer-binding protein β regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes." in: The Journal of biological chemistry, Vol. 289, Issue 5, pp. 2852-63, (2014) (PubMed).

  • 抗原

    RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

    别名

    RUNX2

    背景

    Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).

    分子量

    56648

    NCBI登录号

    NP_001015051, NP_001019801

    UniProt

    Q13950
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