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HES1 抗体 (AA 102-137)

This anti-HES1 antibody is a 兔 多克隆 antibody detecting HES1 in WB. Suitable for 小鼠.
产品编号 ABIN6242801
发货至: 中国

Quick Overview for HES1 抗体 (AA 102-137) (ABIN6242801)

抗原

See all HES1 抗体
HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

适用

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小鼠

宿主

  • 68
  • 17
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克隆类型

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多克隆

标记

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This HES1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB50935
  • 抗原表位

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    AA 102-137

    预测反应

    X, B, H, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of Mouse Hes1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

    别名

    Hes1

    背景

    Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).

    分子量

    29749

    UniProt

    P35428

    途径

    DNA Damage Repair
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