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ZCCHC11 抗体 (C-Term)

ZCCHC11 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51164 unconjugated
产品编号 ABIN6242704
发货至: 中国
  • 抗原 See all ZCCHC11 抗体
    ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))
    抗原表位
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1568-1600, C-Term
    适用
    • 15
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 13
    • 2
    • 2
    克隆类型
    • 17
    多克隆
    标记
    • 17
    This ZCCHC11 antibody is un-conjugated
    应用范围
    • 15
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This (Mouse) Zcchc11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1568-1600 amino acids from the C-terminal region of (Mouse) Zcchc11.
    克隆位点
    RB51164
    亚型
    Ig Fraction
    Top Product
    Discover our top product ZCCHC11 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))
    别名
    Zcchc11 (ZCCHC11 产品)
    别名
    PAPD3 antibody, TUT4 antibody, ZCCHC11 antibody, DKFZp459G145 antibody, 6030404K05Rik antibody, 9230115F04Rik antibody, PPAPD3 antibody, mKIAA0191 antibody, wu:fc06h08 antibody, wu:fy37g11 antibody, papd3 antibody, zinc finger CCHC-type containing 11 antibody, zinc finger, CCHC domain containing 11 antibody, zinc finger CCHC domain containing 11 antibody, ZCCHC11 antibody, Zcchc11 antibody, zcchc11 antibody
    背景
    Uridylyltransferase that acts as a suppressor of microRNA (miRNA) biogenesis by specifically mediating the terminal uridylation of some miRNAs. Catalyzes the 3' uridylation of precursor let-7 (pre-let-7), a miRNA precursor. Uridylated pre- let-7 miRNAs fail to be processed by Dicer and undergo degradation. Degradation of pre-let-7 contributes to the maintenance of embryonic stem (ES) cells and is required for ES cells to maintain pluripotency. Does not bind RNA by itself, recruited to pre-let-7 miRNAs via its interaction with LIN28A and LIN28B (By similarity). Also catalyzes the 3' uridylation of miR- 26A, a miRNA that represses IL6 transcript, leading to abrogate IL6 transcript repression and promote cytokine expression. May also suppress Toll-like receptor-induced NF-kappa-B activity via binding to T2BP. Does not play a role in replication-dependent histone mRNA degradation (By similarity).
    分子量
    184650
    UniProt
    B2RX14
    途径
    Stem Cell Maintenance
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