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- 抗原 See all SMARCC1 抗体
- SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))
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抗原表位
- AA 963-997, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This (Mouse) Smarcc1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 963-997 amino acids from the C-terminal region of (Mouse) Smarcc1.
- 克隆位点
- RB51150
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SMARCC1 Primary Antibody
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (AA 80-320) antibody
SMARCC1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (AA 338-437) antibodySMARCC1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (N-Term) antibodySMARCC1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (AA 783-817), (C-Term) antibodySMARCC1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB51117 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (AA 80-320) antibodySMARCC1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (AA 963-997), (C-Term) antibodySMARCC1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB52817 unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (AA 828-877) antibodySMARCC1 适用: 人, 大鼠, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) antibodySMARCC1 适用: 人, 大鼠, 小鼠 WB, IP, IHC, ChIP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF: 1:25. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))
- 别名
- Smarcc1 (SMARCC1 产品)
- 别名
- smarcc1 antibody, MGC53976 antibody, BAF155 antibody, CRACC1 antibody, Rsc8 antibody, SRG3 antibody, SWI3 antibody, AI115498 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 L homeolog antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 antibody, smarcc1.L antibody, smarcc1a antibody, SMARCC1 antibody, Smarcc1 antibody
- 背景
- Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene (By similarity). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron- specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
- 分子量
- 122890
- UniProt
- P97496
- 途径
- Chromatin Binding
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