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WWP2 抗体 (N-Term)

WWP2 适用: 人 WB 宿主: 兔 Polyclonal RB51426 unconjugated
产品编号 ABIN6242488
发货至: 中国
  • 抗原 See all WWP2 抗体
    WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
    抗原表位
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 218-252, N-Term
    适用
    • 32
    • 10
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 28
    • 4
    克隆类型
    • 31
    • 1
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    This WWP2 antibody is un-conjugated
    应用范围
    • 24
    • 13
    • 9
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This WWP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 218-252 amino acids from the N-terminal region of human WWP2.
    克隆位点
    RB51426
    亚型
    Ig Fraction
    Top Product
    Discover our top product WWP2 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
    别名
    WWP2 (WWP2 产品)
    别名
    aip2 antibody, wwp2-like antibody, id:ibd1121 antibody, wu:fo87e10 antibody, zgc:154036 antibody, AIP2 antibody, WWp2-like antibody, 1300010O06Rik antibody, AA690238 antibody, AW554328 antibody, WW domain containing E3 ubiquitin protein ligase 2 antibody, WWP2 antibody, wwp2 antibody, Wwp2 antibody
    背景
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation, in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation, in T-cells the ubiquitination inhibits activation- induced cell death. Ubiquitinates SLC11A2, the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
    分子量
    98912
    UniProt
    O00308
    途径
    Negative Regulation of Transporter Activity
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