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- 抗原 See all NR4A3 抗体
- NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))
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抗原表位
- AA 254-288
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR4A3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TEC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 254-288 amino acids from the Central region of human TEC.
- 克隆位点
- RB51015
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NR4A3 Primary Antibody
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anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (AA 1-280) antibody
NR4A3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (AA 414-521) antibodyNR4A3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (AA 175-205) antibodyNR4A3 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB03266 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (AA 612-631) antibodyNR4A3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (C-Term) antibodyNR4A3 适用: 人, 犬, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (Modulating Domain) antibodyNR4A3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) antibodyNR4A3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (Internal Region) antibodyNR4A3 适用: 人, 兔, Cow, Pig, 犬, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) antibodyNR4A3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3) (AA 612-631), (C-Term) antibodyNR4A3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))
- 别名
- TEC (NR4A3 产品)
- 别名
- CHN antibody, CSMF antibody, MINOR antibody, NOR1 antibody, TEC antibody, AI573420 antibody, NOR-1 antibody, Nor1 antibody, NOR-2 antibody, NR4A3 antibody, Nr4a3 antibody, nuclear receptor subfamily 4 group A member 3 antibody, nuclear receptor subfamily 4, group A, member 3 antibody, NR4A3 antibody, Nr4a3 antibody, nr4a3 antibody
- 背景
- Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction. Phosphorylates DOK1, one CD28-specific substrate, and contributes to CD28-signaling. Mediates signals that negatively regulate IL2RA expression induced by TCR cross-linking. Plays a redundant role to BTK in BCR-signaling for B-cell development and activation, especially by phosphorylating STAP1, a BCR-signaling protein. Required in mast cells for efficient cytokine production. Involved in both growth and differentiation mechanisms of myeloid cells through activation by the granulocyte colony-stimulating factor CSF3, a critical cytokine to promoting the growth, differentiation, and functional activation of myeloid cells. Participates in platelet signaling downstream of integrin activation. Cooperates with JAK2 through reciprocal phosphorylation to mediate cytokine-driven activation of FOS transcription. GRB10, a negative modifier of the FOS activation pathway, is another substrate of TEC. TEC is involved in G protein-coupled receptor- and integrin-mediated signalings in blood platelets. Plays a role in hepatocyte proliferation and liver regeneration and is involved in HGF-induced ERK signaling pathway. TEC regulates also FGF2 unconventional secretion (endoplasmic reticulum (ER)/Golgi-independent mechanism) under various physiological conditions through phosphorylation of FGF2 'Tyr-215'. May also be involved in the regulation of osteoclast differentiation.
- 分子量
- 73581
- UniProt
- P42680
- 途径
- Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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