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Tuberin 抗体 (pThr1462)

This anti-Tuberin antibody is a 兔 多克隆 antibody detecting Tuberin in DB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6241057
发货至: 中国

Quick Overview for Tuberin 抗体 (pThr1462) (ABIN6241057)

抗原

See all Tuberin (TSC2) 抗体
Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Tuberin antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB13340
  • 抗原表位

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    pThr1462

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1462 of human TSC2.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wu, Storey: "Regulation of the mTOR signaling network in hibernating thirteen-lined ground squirrels." in: The Journal of experimental biology, Vol. 215, Issue Pt 10, pp. 1720-7, (2012) (PubMed).

  • 抗原

    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

    别名

    TSC2

    背景

    Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

    分子量

    200608

    NCBI登录号

    NP_000539, NP_001070651, NP_001107854

    UniProt

    P49815

    途径

    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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