Tuberin 抗体 (pThr1462)
Quick Overview for Tuberin 抗体 (pThr1462) (ABIN6241057)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pThr1462
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1462 of human TSC2.
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亚型
- Ig Fraction
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Regulation of the mTOR signaling network in hibernating thirteen-lined ground squirrels." in: The Journal of experimental biology, Vol. 215, Issue Pt 10, pp. 1720-7, (2012) (PubMed).
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Regulation of the mTOR signaling network in hibernating thirteen-lined ground squirrels." in: The Journal of experimental biology, Vol. 215, Issue Pt 10, pp. 1720-7, (2012) (PubMed).
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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别名
- TSC2
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背景
- Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.
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分子量
- 200608
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NCBI登录号
- NP_000539, NP_001070651, NP_001107854
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UniProt
- P49815
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途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
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