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MYB 抗体 (AA 119-135) (CF®488A)

MYB 适用: 人 IF, FACS 宿主: 小鼠 Monoclonal MYB286 CF®488A
产品编号 ABIN6188381
发货至: 中国
  • 抗原 See all MYB 抗体
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    抗原表位
    • 15
    • 11
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
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    • 2
    • 2
    • 2
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 119-135
    适用
    • 114
    • 52
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 96
    • 20
    • 3
    • 2
    小鼠
    克隆类型
    • 102
    • 19
    单克隆
    标记
    • 78
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This MYB antibody is conjugated to CF®488A
    应用范围
    • 93
    • 56
    • 44
    • 23
    • 22
    • 13
    • 13
    • 11
    • 9
    • 5
    • 3
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    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-c-Myb (MYB286), CF488A Conjugate
    产品特性
    The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
    克隆位点
    MYB286
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MYB Primary Antibody
  • 应用备注
    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    别名
    c-Myb (MYB 产品)
    别名
    Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody
    背景
    C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog
    分子量
    75 kDa
    基因ID
    4602, 606320
    UniProt
    P01104
    途径
    Chromatin Binding, Positive Regulation of Immune Effector Process
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