MYB 抗体 (AA 119-135) (CF®488A)
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- 抗原 See all MYB 抗体
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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抗原表位
- AA 119-135
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MYB antibody is conjugated to CF®488A
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-c-Myb (MYB286), CF488A Conjugate
- 产品特性
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
- 克隆位点
- MYB286
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MYB Primary Antibody
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- 应用备注
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
- 别名
- c-Myb (MYB 产品)
- 别名
- Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody
- 背景
- C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog
- 分子量
- 75 kDa
- 基因ID
- 4602, 606320
- UniProt
- P01104
- 途径
- Chromatin Binding, Positive Regulation of Immune Effector Process
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