电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

GP2 抗体 (AA 35-179) (CF®640R)

GP2 适用: 人 IHC, FACS, IF, ISt 宿主: 小鼠 Monoclonal GP2-1712 CF®640R
产品编号 ABIN6187109
发货至: 中国
  • 抗原 See all GP2 products
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    抗原表位
    • 28
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 35-179
    适用
    • 48
    • 8
    • 4
    • 2
    • 2
    • 1
    宿主
    • 32
    • 25
    小鼠
    克隆类型
    • 29
    • 28
    单克隆
    标记
    • 29
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GP2 antibody is conjugated to CF®640R
    应用范围
    • 34
    • 32
    • 23
    • 19
    • 19
    • 13
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunostaining (ISt)
    原理
    Mouse Monoclonal anti-GP2 / ZAP75 (GP2/1712), CF640R Conjugate
    产品特性
    GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human GP2 protein fragment (aa35-179) (exact sequence is proprietary)
    克隆位点
    GP2-1712
    亚型
    IgG
  • 应用备注
    Immunohistology (formalin) 1-2 μg/mL
    • Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    PANC-1 cells. Pancreas

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    别名
    GP2 / ZAP75 (GP2 产品)
    别名
    ZAP75 antibody, 2310037I18Rik antibody, AV060639 antibody, gp80 antibody, glycoprotein 2 antibody, glycoprotein 2 (zymogen granule membrane) antibody, GP2 antibody, Gp2 antibody
    物质类
    Viral Protein
    背景
    Glycoprotein 2 (zymogen granule membrane), GP2, Pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
    分子量
    59 kDa
    基因ID
    2813, 53985
    UniProt
    P55259
You are here:
客服