GP2 抗体 (AA 35-179) (CF®640R)
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- 抗原 See all GP2 products
- GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
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抗原表位
- AA 35-179
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GP2 antibody is conjugated to CF®640R
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应用范围
- ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)
- 原理
- Mouse Monoclonal anti-GP2 / ZAP75 (GP2/1551), CF640R Conjugate
- 产品特性
- GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human GP2 protein fragment (aa35-179) (exact sequence is proprietary)
- 克隆位点
- GP2-1551
- 亚型
- IgG2b lambda
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- 应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- ELISA For coating, order Ab without BSA
- Optimal dilution for a specific application should be determined by user
- 说明
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PANC-1 cells. Pancreas
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
- 别名
- GP2 / ZAP75 (GP2 产品)
- 别名
- ZAP75 antibody, 2310037I18Rik antibody, AV060639 antibody, gp80 antibody, glycoprotein 2 antibody, glycoprotein 2 (zymogen granule membrane) antibody, GP2 antibody, Gp2 antibody
- 物质类
- Viral Protein
- 背景
- Glycoprotein 2 (zymogen granule membrane), GP2, Pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
- 分子量
- 59 kDa
- 基因ID
- 2813, 53985
- UniProt
- P55259
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