HCG beta 抗体
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- 抗原 See all HCG beta 抗体
- HCG beta
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HCG beta antibody is un-conjugated
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应用范围
- Immunohistochemistry (Frozen Sections) (IHC (fro))
- 原理
- Mouse Monoclonal anti-HCG beta (HCGb/211), Purified, with BSA
- 产品特性
- This MAb reacts with a protein of 22 kDa, identified as β sub-unit of HCG. It does not cross react with the α sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Purified human HCG-beta
- 克隆位点
- HCGb-211
- 亚型
- IgG1
- Top Product
- Discover our top product HCG beta Primary Antibody
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- 应用备注
- Immunohistology (frozen) 0.5-1 μg/mL
- 说明
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Placenta
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 200 μg/mL
- 缓冲液
- PBS/0.05 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- HCG beta
- Abstract
- HCG beta 产品
- 背景
- CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB
- 分子量
- 22 kDa
- 基因ID
- 1082, 172944
- UniProt
- P01233
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