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CNN1 抗体

CNN1 适用: 人, 大鼠 FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal CNN1-832 unconjugated
产品编号 ABIN6178287
发货至: 中国
  • 抗原 See all CNN1 抗体
    CNN1 (Calponin 1 (CNN1))
    适用
    • 84
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    • 1
    • 1
    • 1
    • 1
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    • 1
    人, 大鼠
    宿主
    • 45
    • 37
    • 2
    小鼠
    克隆类型
    • 54
    • 30
    单克隆
    标记
    • 41
    • 5
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    • 4
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    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This CNN1 antibody is un-conjugated
    应用范围
    • 60
    • 46
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    • 33
    • 21
    • 13
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    • 5
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    • 3
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    原理
    Mouse Monoclonal anti-Calponin-1 (CNN1/832), Purified, BSA-free
    产品特性
    Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant human CNN1 protein
    克隆位点
    CNN1-832
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CNN1 Primary Antibody
  • 应用备注
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Myoepithelial cells in breast ducts

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    CNN1 (Calponin 1 (CNN1))
    别名
    Calponin-1 (CNN1 产品)
    别名
    CN antibody, CnnI antibody, SMCC antibody, Sm-Calp antibody, XclpH3 antibody, clpH3 antibody, cnn2 antibody, calponin 1 antibody, calponin 1, basic, smooth muscle L homeolog antibody, cnn1 antibody, Cnn1 antibody, CNN1 antibody, cnn1.L antibody
    背景
    Calponin 1 basic smooth muscle, Calponin H1 smooth muscle, Calponin-1, CNN1, Cnn1, Sm Calp, SMCC
    分子量
    34 kDa
    基因ID
    1264, 465929
    UniProt
    P51911
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