CFTR 抗体 (AA 258-385) (CF®568)
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- 抗原 See all CFTR 抗体
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
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抗原表位
- AA 258-385
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CFTR antibody is conjugated to CF®568
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC), Immunostaining (ISt)
- 原理
- Mouse Monoclonal anti-CFTR CFTR/1785), CF568 Conjugate
- 产品特性
- This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human CFTR fragment (aa258-385) (exact sequence is proprietary)
- 克隆位点
- CFTR-1785
- 亚型
- IgG2b
- Top Product
- Discover our top product CFTR Primary Antibody
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anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) antibody
CFTR 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (AA 258-385) antibodyCFTR 适用: 人 IHC (f), FACS 宿主: 小鼠 Monoclonal CFTR-1643 unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (AA 1161-1480) antibodyCFTR 适用: 人 IF, WB 宿主: 兔 Polyclonal unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) antibodyCFTR 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) antibodyCFTR 适用: 人 ISt, IHC (f) 宿主: 小鼠 Monoclonal CFTR-1342 unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (Ser246) antibodyCFTR 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (AA 258-385) antibodyCFTR 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal unconjugated
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (AA 258-385) antibodyCFTR 适用: 人 ISt, IHC (f) 宿主: 兔 Monoclonal CFTR-1775R unconjugated Recombinant Antibody
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) antibodyCFTR 适用: 人 ISt, IHC (f) 宿主: 小鼠 Monoclonal rCFTR-1342 unconjugated Recombinant Antibody
anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) (AA 258-385) antibodyCFTR 适用: 人 ISt, IHC (f) 宿主: 小鼠 Monoclonal CFTR-1785 unconjugated
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- 应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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MOLT-4 cells. Pancreas, Kidney or Placenta.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
- 别名
- CFTR (CFTR 产品)
- 别名
- ABC35 antibody, ABCC7 antibody, CF antibody, CFTR/MRP antibody, MRP7 antibody, TNR-CFTR antibody, dJ760C5.1 antibody, CFTR antibody, AW495489 antibody, Abcc7 antibody, RGD1561193 antibody, abc35 antibody, abcc7 antibody, cftr/mrp antibody, mrp7 antibody, tnr-cftr antibody, xcftr antibody, si:dkey-270i2.2 antibody, cystic fibrosis transmembrane conductance regulator antibody, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) antibody, CFTR antibody, cftr-A antibody, Cftr antibody, cftr antibody
- 分子量
- 165-170 kDa
- 基因ID
- 1080
- UniProt
- P13569
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