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CFTR 抗体

CFTR 适用: 人, 小鼠 IF, IHC, ISt, WB 宿主: 小鼠 Monoclonal CFTR-1342 unconjugated
产品编号 ABIN6174638
发货至: 中国
  • 抗原 See all CFTR 抗体
    CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
    适用
    • 104
    • 38
    • 26
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 58
    • 46
    小鼠
    克隆类型
    • 67
    • 37
    单克隆
    标记
    • 55
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CFTR antibody is un-conjugated
    应用范围
    • 59
    • 47
    • 44
    • 42
    • 22
    • 18
    • 9
    • 9
    • 9
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (IHC), Immunostaining (ISt), Western Blotting (WB)
    原理
    Mouse Monoclonal anti-CFTR CFTR/1342), Purified, with BSA
    产品特性
    This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant human full-length CFTR
    克隆位点
    CFTR-1342
    亚型
    IgG2a
    Top Product
    Discover our top product CFTR Primary Antibody
  • 应用备注
    Immunohistology (formalin) 0.5-1 μg/mL
    • Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    MOLT-4 cells. Pancreas, Kidney or Placenta.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    200 μg/mL
    缓冲液
    PBS/0.05 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
    别名
    CFTR (CFTR 产品)
    别名
    ABC35 antibody, ABCC7 antibody, CF antibody, CFTR/MRP antibody, MRP7 antibody, TNR-CFTR antibody, dJ760C5.1 antibody, CFTR antibody, AW495489 antibody, Abcc7 antibody, RGD1561193 antibody, abc35 antibody, abcc7 antibody, cftr/mrp antibody, mrp7 antibody, tnr-cftr antibody, xcftr antibody, si:dkey-270i2.2 antibody, cystic fibrosis transmembrane conductance regulator antibody, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) antibody, CFTR antibody, cftr-A antibody, Cftr antibody, cftr antibody
    分子量
    165-170 kDa
    基因ID
    1080
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