UACA 抗体
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- 抗原 See all UACA 抗体
- UACA
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This UACA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-UACA / Nucling (AE-5), Purified, BSA-free
- 产品特性
- UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Nuclei of myeloid leukemia biopsy cells
- 克隆位点
- AE-5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product UACA Primary Antibody
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anti-UACA (UACA) (AA 29-209) antibody
UACA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-UACA (UACA) (AA 1-90) antibodyUACA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UACA (UACA) antibodyUACA 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UACA (UACA) (AA 1309-1358) antibodyUACA 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-UACA (UACA) antibodyUACA 适用: 人, 小鼠 WB, IF, FACS 宿主: 小鼠 Monoclonal AE-5 unconjugated
anti-UACA (UACA) (AA 1-1416) antibodyUACA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 0.5-1.0 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
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- 抗原
- UACA
- 别名
- UACA / Nucling (UACA 产品)
- 别名
- NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody
- 背景
- Nuclear membrane binding protein, Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), NUCLING
- 分子量
- 160 kDa
- 基因ID
- 55075, 108049
- UniProt
- Q9BZF9
- 途径
- Positive Regulation of Endopeptidase Activity
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