TOX3 抗体 (AA 200-400)
-
- 抗原 See all TOX3 抗体
- TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
-
抗原表位
- AA 200-400
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TOX3 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Mouse Monoclonal anti-TOX3 (TOX3/1123), Purified, BSA-free
- 产品特性
- This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2 -dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
- 克隆位点
- TOX3-1123
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TOX3 Primary Antibody
-
anti-TOX High Mobility Group Box Family Member 3 (TOX3) (AA 214-242) antibody
TOX3 适用: 人, 小鼠 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB24743 unconjugated
anti-TOX High Mobility Group Box Family Member 3 (TOX3) (AA 8-305) antibodyTOX3 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TOX High Mobility Group Box Family Member 3 (TOX3) (AA 251-389) antibodyTOX3 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TOX3-1124 unconjugated
anti-TOX High Mobility Group Box Family Member 3 (TOX3) (AA 200-400) antibodyTOX3 适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal TOX3-1123 unconjugated
-
- 应用备注
-
Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 or 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- 说明
-
SH-SY5Y, MDA-MB-435 cells. Brain or breast or gastric Carcinoma.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
-
- 抗原
- TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))
- 别名
- TOX3 (TOX3 产品)
- 别名
- TNRC9 antibody, cagf9 antibody, tnrc9 antibody, CAGF9 antibody, 500-9 antibody, BC052044 antibody, C230068E13 antibody, Tnrc9 antibody, TOX high mobility group box family member 3 antibody, TOX3 antibody, tox3 antibody, Tox3 antibody
- 背景
- TOX3, CAG trinucleotide repeat-containing gene F9 protein, CAGF9, TOX high mobility group box family member 3, Trinucleotide repeat containing 9 (TNRC9)
- 分子量
- 63 kDa
- 基因ID
- 27324, 460789
- UniProt
- O15405
- 途径
- Chromatin Binding
-
