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Transgelin 抗体 (CF®594)

TAGLN 适用: 人, 小鼠, Cow, 兔, Pig FACS, IF 宿主: 小鼠 Monoclonal TAGLN-247 CF®594
产品编号 ABIN6167728
发货至: 中国
  • 抗原 See all Transgelin (TAGLN) 抗体
    Transgelin (TAGLN)
    适用
    • 69
    • 22
    • 13
    • 13
    • 12
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, Cow, 兔, Pig
    宿主
    • 44
    • 24
    • 3
    • 1
    小鼠
    克隆类型
    • 48
    • 24
    单克隆
    标记
    • 43
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Transgelin antibody is conjugated to CF®594
    应用范围
    • 38
    • 29
    • 26
    • 22
    • 19
    • 15
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Mouse Monoclonal anti-Transgelin / SM22-alpha (TAGLN/247), CF594 Conjugate
    产品特性
    This MAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is down regulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant full-length human transgelin (TAGLN) protein.
    克隆位点
    TAGLN-247
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TAGLN Primary Antibody
  • 应用备注
    Flow Cytometry 0.5-1 μg/million cells/0.1 mLImmunofluorescence 1-2 μg/mL
    说明

    U-2 OS, Hs68 or WI 38 cells. Colon carcinoma.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    Transgelin (TAGLN)
    别名
    Transgelin / SM22-alpha (TAGLN 产品)
    别名
    MGC68550 antibody, sm22 antibody, smcc antibody, tagln1 antibody, ws3-10 antibody, MGC107855 antibody, SM22 antibody, SMCC antibody, TAGLN1 antibody, WS3-10 antibody, Sm22 antibody, Sm22a antibody, Ws310 antibody, SM22A antibody, zgc:153186 antibody, transgelin L homeolog antibody, transgelin antibody, tagln.L antibody, tagln antibody, LOC732906 antibody, TAGLN antibody, tagl antibody, LOC100009332 antibody, Tagln antibody
    分子量
    22 kDa
    基因ID
    6876, 410977
    UniProt
    Q01995
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