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PTH 抗体 (C-Term) (CF®594)

PTH 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal PTH-1173 CF®594
产品编号 ABIN6166663
发货至: 中国
  • 抗原 See all PTH 抗体
    PTH (Parathyroid Hormone (PTH))
    抗原表位
    • 30
    • 26
    • 19
    • 13
    • 11
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 160
    • 9
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 100
    • 72
    • 13
    • 2
    小鼠
    克隆类型
    • 98
    • 87
    单克隆
    标记
    • 115
    • 20
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTH antibody is conjugated to CF®594
    应用范围
    • 69
    • 65
    • 57
    • 47
    • 40
    • 26
    • 23
    • 16
    • 14
    • 9
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-PTH / Parathyroid Hormone (N-Terminal) (PTH/1173), CF594 Conjugate
    产品特性
    The epitope of this MAb maps in the C-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2 levels by dissolving the salts in bone and preventing their renal excretion.It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant fragment (84 amino acid residues from C-terminus) of human PTH protein
    克隆位点
    PTH-1173
    亚型
    IgG2b kappa
    Top Product
    Discover our top product PTH Primary Antibody
  • 应用备注
    Immunohistology (formalin)
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Human parathyroid gland carcinoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    PTH (Parathyroid Hormone (PTH))
    别名
    PTH / Parathyroid Hormone (PTH 产品)
    别名
    PTH1 antibody, Pthp antibody, PTH-(1-84) antibody, Pth1 antibody, Pthr1 antibody, PTH antibody, parathyroid hormone antibody, parathyroid hormone S homeolog antibody, PTH antibody, Pth antibody, pth.S antibody
    物质类
    Hormone
    背景
    HPTH, Parathormone, Parathyrin, Parathyroid hormone 1 (PTH1), Parathyroid hormone (PTH)
    分子量
    9 kDa
    基因ID
    5741, 37045
    UniProt
    P01270
    途径
    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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