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SELPLG 抗体 (CF®405S)

SELPLG 适用: 人 FACS, IHC, IF, ISt 宿主: 小鼠 Monoclonal PSGL1-1601 CF®405S
产品编号 ABIN6157938
发货至: 中国
  • 抗原 See all SELPLG 抗体
    SELPLG (Selectin P Ligand (SELPLG))
    适用
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    小鼠
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    单克隆
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    This SELPLG antibody is conjugated to CF®405S
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt)
    原理
    Mouse Monoclonal anti-CD162 (PSGL1/1601), CF405S Conjugate
    产品特性
    CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant human full-length SELPLG (CD162) protein
    克隆位点
    PSGL1-1601
    亚型
    IgG1
    Top Product
    Discover our top product SELPLG Primary Antibody
  • 应用备注
    Immunohistology (formalin) 1-2 μg/mL
    • Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Jurkat cells. Tonsil or Spleen

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    SELPLG (Selectin P Ligand (SELPLG))
    别名
    CD162 (SELPLG 产品)
    别名
    CD162 antibody, CLA antibody, PSGL-1 antibody, PSGL1 antibody, SELPLG antibody, SELPG antibody, Psgl-1 antibody, Psgl1 antibody, Selp1 antibody, Selpl antibody, selectin P ligand antibody, selectin, platelet (p-selectin) ligand antibody, clasper antibody, SELPLG antibody, Selplg antibody, cla antibody
    背景
    CD162, CLA, Cutaneous lymphocyte associated antigen, P-selectin glycoprotein lig, 1, PSGL1, Selectin P lig, SELPLG
    分子量
    43-120 kDa
    基因ID
    6404, 591014
    UniProt
    Q14242
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