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Alkaline Phosphatase 抗体

ALP 适用: 人, Cow IF, FACS, IHC (f) 宿主: 小鼠 Monoclonal ALPL-597 unconjugated
产品编号 ABIN6155884
发货至: 中国
  • 抗原 See all Alkaline Phosphatase (ALP) 抗体
    Alkaline Phosphatase (ALP)
    适用
    • 51
    • 23
    • 12
    • 12
    • 11
    • 1
    人, Cow
    宿主
    • 56
    • 15
    • 4
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 54
    • 25
    单克隆
    标记
    • 42
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Alkaline Phosphatase antibody is un-conjugated
    应用范围
    • 50
    • 34
    • 22
    • 19
    • 11
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    原理
    Mouse Monoclonal anti-Alkaline Phosphatase (ALPL/597), Purified, BSA-free
    产品特性
    This antibody reacts with tissue non-specific alkaline phosphatase. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. Primary antibodies are available purified, or with a selection of fluorescent CF ® dyes and other labels. CF ® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF ®405S and CF ®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Recombinant human ALP1 protein
    克隆位点
    ALPL-597
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ALP Primary Antibody
  • 应用备注
    Flow Cytometry 5-10 uL/million cells in 0.1 mL
    • Immunohistology formalin-fixed 1:50-1:100
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 1:50-1:100
    • Optimal dilution for a specific application should be determined by user
    说明

    Intestine

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    Alkaline Phosphatase (ALP)
    别名
    Alkaline Phosphatase (ALP 产品)
    别名
    ALP antibody, ALP1 antibody, CRASH antibody, ECK0378 antibody, JW0374 antibody, psiA antibody, 2410004D18Rik antibody, AU040643 antibody, AW060375 antibody, ILC antibody, CTACK antibody, ESkine antibody, Akp2 antibody, alp antibody, zgc:56672 antibody, DDBDRAFT_0205491 antibody, DDBDRAFT_0231570 antibody, DDB_0205491 antibody, DDB_0231570 antibody, Actn2lp antibody, Alp antibody, asparaginase like 1 antibody, bacterial alkaline phosphatase antibody, C-C motif chemokine ligand 27 antibody, alkaline phosphatase, liver/bone/kidney antibody, alkaline phosphatase antibody, PDZ and LIM domain 3 antibody, ASRGL1 antibody, phoA antibody, Asrgl1 antibody, CCL27 antibody, alpl antibody, alp antibody, Pdlim3 antibody
    分子量
    55 kDa
    基因ID
    248, 284255, 333509
    UniProt
    P05186, P05187
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