Ku-Holo (p70,83) 抗体 (CF®647)
适用: 人, Non-Human Primate
FACS, ICC, IF
宿主: 小鼠
Monoclonal
KU729
CF®647
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- 抗原
- Ku-Holo (p70,83)
- 适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- CF®647
- 应用范围
- Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 原理
- Mouse Monoclonal anti-Ku-Holo (p70,83) (KU729), CF647 Conjugate
- 产品特性
- This antibody recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Primary antibodies are available purified, or with a selection of fluorescent CF ® dyes and other labels. CF ® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF ®405S and CF ®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Nuclear extract of human HL-60 cells
- 克隆位点
- KU729
- 亚型
- IgG1 kappa
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- 应用备注
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Immunocytochemistry acetone-fixed cells 0.25-0.5 μg/mL
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Does not react with mouse, rat or chicken, others not known
- Optimal dilution for a specific application should be determined by user
- 说明
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Human cancer K562, HL-60, HEp-2 or HeLa cells
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- Ku-Holo (p70,83)
- 分子量
- 70 kDa & 80 kDa
- 基因ID
- 2547, 7520
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