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BAK1 抗体 (N-Term)

BAK1 适用: 人, 小鼠, Hamster IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN615093
发货至: 中国
  • 抗原 See all BAK1 抗体
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    抗原表位
    • 19
    • 16
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 76
    • 32
    • 23
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, Hamster
    宿主
    • 71
    • 3
    • 2
    • 1
    克隆类型
    • 64
    • 13
    多克隆
    标记
    • 43
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAK1 antibody is un-conjugated
    应用范围
    • 66
    • 27
    • 26
    • 17
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody recognizes BCL2-antagonist/killer 1 (BAK1).
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide derived from N-terminal of Human Bcl-2-like 7. Genename: BAK1
    Top Product
    Discover our top product BAK1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    别名
    Bcl-2-Like 7 (BAK1 产品)
    别名
    BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
    背景
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability.Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1
    基因ID
    578
    NCBI登录号
    NP_001179
    UniProt
    Q16611
    途径
    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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