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BAK1 抗体 (N-Term)

The 兔 多克隆 anti-BAK1 antibody (ABIN615093) specifically detects BAK1 in IHC (p). The antibody is reactive with 人, 小鼠 和 Hamster samples.
产品编号 ABIN615093
发货至: 中国
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Quick Overview for BAK1 抗体 (N-Term) (ABIN615093)

抗原

See all BAK1 抗体
BAK1 (BCL2-Antagonist/killer 1 (BAK1))

适用

  • 87
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  • 16
  • 2
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  • 1
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  • 1
人, 小鼠, Hamster

宿主

  • 80
  • 7
  • 2

克隆类型

  • 61
  • 28
多克隆

标记

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  • 6
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  • 1
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This BAK1 antibody is un-conjugated

应用范围

  • 73
  • 34
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  • 28
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  • 19
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  • 13
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  • 4
  • 3
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
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    N-Term

    特异性

    This antibody recognizes BCL2-antagonist/killer 1 (BAK1).

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide derived from N-terminal of Human Bcl-2-like 7. Genename: BAK1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原

    BAK1 (BCL2-Antagonist/killer 1 (BAK1))

    别名

    Bcl-2-Like 7

    背景

    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability.Synonyms: Apoptosis regulator BAK, BAK, BAK1, BCL2L7, Bcl-2 homologous antagonist/killer, Bcl-2-like protein 7, Bcl2-L-7, CDN1, cell death inhibitor 1

    基因ID

    578

    NCBI登录号

    NP_001179

    UniProt

    Q16611

    途径

    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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