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CXCR4 抗体 (Extracellular Domain, N-Term)

CXCR4 适用: 人, 小鼠, 非洲爪蟾 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN614959
发货至: 中国
  • 抗原 See all CXCR4 抗体
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    抗原表位
    • 23
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    AA 14-40, Extracellular Domain, N-Term
    适用
    • 141
    • 89
    • 72
    • 20
    • 11
    • 9
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    • 6
    • 4
    • 3
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    • 3
    • 3
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    • 1
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    人, 小鼠, 非洲爪蟾
    宿主
    • 121
    • 20
    • 10
    • 6
    • 1
    山羊
    克隆类型
    • 130
    • 28
    多克隆
    标记
    • 90
    • 8
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    • 6
    • 5
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    This CXCR4 antibody is un-conjugated
    应用范围
    • 115
    • 55
    • 45
    • 34
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    • 25
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    • 24
    • 18
    • 11
    • 7
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    YSEEVGSGDY DSNKEPCFRD ENVHFNR
    特异性
    This antibody binds to CXCR4 receptor on Mouse spleen leukocytes as determined by Immunocytochemistry.
    交叉反应 (详细)
    Species reactivity (expected):Xenopus, Human.
    Species reactivity (tested):Mouse
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Sequence corresponding to the N-terminal extracellular domain of Mouse CXCR4 receptor. Epitope: aa14-40 Genename: CXCR4
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide, 1 mg/mL BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    别名
    CD184 / CXCR4 (CXCR4 产品)
    别名
    CD184 antibody, D2S201E antibody, FB22 antibody, HM89 antibody, HSY3RR antibody, LAP3 antibody, LCR1 antibody, LESTR antibody, NPY3R antibody, NPYR antibody, NPYRL antibody, NPYY3R antibody, WHIM antibody, Cmkar4 antibody, PB-CKR antibody, PBSF/SDF-1 antibody, Sdf1r antibody, CXC-R4-B antibody, CXCR-4-B antibody, cd184 antibody, cxcr4 antibody, fb22 antibody, hm89 antibody, hsy3rr antibody, lap3 antibody, lcr1 antibody, lestr antibody, npy3r antibody, npyr antibody, npyrl antibody, npyy3r antibody, xcxcr4 antibody, CXC-R4 antibody, CXCR-4 antibody, d2s201e antibody, whim antibody, CXC-R4-A antibody, CXCR-4-A antibody, xCXCR4 antibody, CXCR4 antibody, cb403 antibody, zgc:109863 antibody, cb824 antibody, C-X-C motif chemokine receptor 4 antibody, chemokine (C-X-C motif) receptor 4 antibody, C-X-C motif chemokine receptor 4 S homeolog antibody, C-X-C chemokine receptor type 4 antibody, C-X-C motif chemokine receptor 4 L homeolog antibody, chemokine (C-X-C motif), receptor 4b antibody, chemokine (C-X-C motif) receptor 4a antibody, CXCR4 antibody, Cxcr4 antibody, cxcr4.S antibody, cxcr4 antibody, LOC100049444 antibody, cxcr4.L antibody, cxcr4b antibody, cxcr4a antibody
    背景
    CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.Synonyms: C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, LESTR, Leukocyte-derived seven transmembrane domain receptor, NPYRL, SDF1 receptor, Stromal cell-derived factor 1 receptor
    基因ID
    7852
    NCBI登录号
    NP_001008540
    UniProt
    P61073
    途径
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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