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TP53INP1 抗体 (AA 1-100)

TP53INP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6149422
发货至: 中国
  • 抗原 See all TP53INP1 抗体
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    抗原表位
    • 12
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 55
    • 29
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 62
    克隆类型
    • 52
    • 9
    多克隆
    标记
    • 25
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TP53INP1 antibody is un-conjugated
    应用范围
    • 43
    • 34
    • 31
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MFQRLNKMFV GEVSSSSNQE PEFNEKEDDE WILVDFIDTC TGFSAEEEEE EEDISEESPT EHPSVFSCLP ASLECLADTS DSCFLQFESC PMEESWFITP
    交叉反应
    小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p53 DINP1 (NP_001129205.1).
    亚型
    IgG
    Top Product
    Discover our top product TP53INP1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
    别名
    TP53INP1 (TP53INP1 产品)
    别名
    cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
    背景
    Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.,TP53INP1,SIP,TP53DINP1,TP53INP1A,TP53INP1B,Teap,p53DINP1,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,TP53INP1
    分子量
    18 kDa/27 kDa
    基因ID
    94241
    UniProt
    Q96A56
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