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TANK 抗体 (AA 1-119)

This anti-TANK antibody is a 兔 多克隆 antibody detecting TANK in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6148843
发货至: 中国

Quick Overview for TANK 抗体 (AA 1-119) (ABIN6148843)

抗原

See all TANK 抗体
TANK (TRAF Family Member-Associated NFKB Activator (TANK))

适用

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宿主

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克隆类型

  • 62
多克隆

标记

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This TANK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-119

    序列

    MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV DIASAESSI

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human TANK (NP_597841.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Qian, Fan, Liu, Wu, Zhang, Cui, Zhou, Hu, Wei, Chen, Li, Qian: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." in: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).

  • 抗原

    TANK (TRAF Family Member-Associated NFKB Activator (TANK))

    别名

    TANK

    背景

    The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.,TANK,I-TRAF,ITRAF,TRAF2,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,TNF,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TANK

    分子量

    13 kDa/47 kDa

    基因ID

    10010

    UniProt

    Q92844

    途径

    p53 Pathway, TLR signaling, Activation of Innate immune Response
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