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SPTA1 抗体 (AA 940-1160)

This anti-SPTA1 antibody is a 兔 多克隆 antibody detecting SPTA1 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6148401
发货至: 中国

Quick Overview for SPTA1 抗体 (AA 940-1160) (ABIN6148401)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 67
  • 13
  • 5
  • 1
  • 1
  • 1
  • 1

宿主

  • 39
  • 29

克隆类型

  • 55
  • 13
多克隆

标记

  • 29
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPTA1 antibody is un-conjugated

应用范围

  • 50
  • 48
  • 40
  • 9
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 48
    • 1
    • 1
    • 1
    • 1
    AA 940-1160

    序列

    KHEAFLLDLN SFGDSMKALR NQANACQQQQ AAPVEGVAGE QRVMALYDFQ ARSPREVTMK KGDVLTLLSS INKDWWKVEA ADHQGIVPAV YVRRLAHDEF PMLPQRRREE PGNITQRQEQ IENQYRSLLD RAEERRRRLL QRYNEFLLAY EAGDMLEWIQ EKKAENTGVE LDDVWELQKK FDEFQKDLNT NEPRLRDINK VADDLLFEGL LTPEGAQIRQ E

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human alpha 1 Spectrin (NP_003117.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Talhouarne, Gall: "7SL RNA in vertebrate red blood cells." in: RNA (New York, N.Y.), Vol. 24, Issue 7, pp. 908-914, (2018) (PubMed).

  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    SPTA1

    背景

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.,SPTA1,EL2,HPP,HS3,SPH3,SPTA,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Cardiovascular,Blood,Blood Cell Antigens,SPTA1

    分子量

    279 kDa/280 kDa

    基因ID

    6708

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
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