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小鼠 anti-人 Ig (Chain kappa), (Light Chain) Antibody

FACS Monoclonal TB28-2 IgG1 unconjugated
产品编号 ABIN614821
发货至: 中国
  • 抗原 See all Ig products
    Ig
    抗原表位
    • 76
    • 71
    • 56
    • 32
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Chain kappa, Light Chain
    适用
    • 110
    • 51
    • 24
    • 18
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 94
    • 83
    • 25
    • 18
    • 4
    • 1
    • 1
    小鼠
    克隆类型
    • 115
    • 103
    单克隆
    应用范围
    • 154
    • 134
    • 90
    • 60
    • 47
    • 26
    • 23
    • 13
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein-A affinity chromatography
    免疫原
    Human IgG-kappa myeloma protein
    克隆位点
    TB28-2
    亚型
    IgG1
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Storer the antibody at 2-8 °C for up to one month or (in aliqouts) at -20 °C for longer.
  • Jourdan, Caraux, De Vos, Fiol, Larroque, Cognot, Bret, Duperray, Hose, Klein: "An in vitro model of differentiation of memory B cells into plasmablasts and plasma cells including detailed phenotypic and molecular characterization." in: Blood, Vol. 114, Issue 25, pp. 5173-81, (2009) (PubMed).

    Böttcher, Ritgen, Buske, Gesk, Klapper, Hoster, Hiddemann, Unterhalt, Dreyling, Siebert, Kneba, Pott et al.: "Minimal residual disease detection in mantle cell lymphoma: methods and significance of four-color flow cytometry compared to consensus IGH-polymerase chain reaction at initial staging and for ..." in: Haematologica, Vol. 93, Issue 4, pp. 551-9, (2008) (PubMed).

    Cassens, Göhde, Kuling, Gröning, Schlenke, Lehman, Traoré, Servais, Henin, Reichelt, Greve: "Simplified volumetric flow cytometry allows feasible and accurate determination of CD4 T lymphocytes in immunodeficient patients worldwide." in: Antiviral therapy, Vol. 9, Issue 3, pp. 395-405, (2004) (PubMed).

    Karandikar, Aquino, McKenna, Kroft: "Transient myeloproliferative disorder and acute myeloid leukemia in Down syndrome. An immunophenotypic analysis." in: American journal of clinical pathology, Vol. 116, Issue 2, pp. 204-10, (2001) (PubMed).

    Nakamura, Kubagawa, Cooper: "Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8522-6, (1992) (PubMed).

  • 抗原
    Ig
    别名
    Immunoglobulin (Ig 产品)
    背景
    Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
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