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SMAD2 抗体 (AA 1-100)

Name: SMAD2 抗体 (AA 1-100)
Brand: antibodies-online
SKU: ABIN6148079
Availability: OutOfStock

This anti-SMAD2 antibody is a 兔多克隆 antibody detecting SMAD2 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Western blot analysis of extracts of various cell lines, using SMAD2 antibody. (SMAD2 抗体 (AA 1-100))

Immunohistochemistry of paraffin-embedded mouse spleen using SMAD2 antibody. (SMAD2 抗体 (AA 1-100))

IHC (p)

2 images

(2 references)

产品编号 ABIN6148079

发货至: 中国

Quick Overview for SMAD2 抗体 (AA 1-100) (ABIN6148079)

抗原

See all SMAD2 抗体

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

适用

人

宿主

兔

克隆类型

多克隆

标记

This SMAD2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Discover our top product SMAD2 Primary Antibody

抗原表位
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AA 1-100

序列

MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE LEKAITTQNC NTKCVTIPST CSEIWGLSTP NTIDQWDTTG

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (NP_001003652.1).

亚型

IgG
anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) antibody
SMAD2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer423), (pSer425), (pSer465), (pSer467) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (C-Term) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer467) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pThr183), (pThr221) antibody
SMAD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2D7 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 94-112), (N-Term) antibody
SMAD2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Shao, Song, Hua, Zhang, Sun, Kong, Wang, Luo, Jiang: "Gamma synuclein is a novel Twist1 target that promotes TGF-β-induced cancer cell migration and invasion." in: Cell death & disease, Vol. 9, Issue 6, pp. 625, (2018) (PubMed).

Liu, Zhang, Su, Wang, Liu, Kong: "Effects of cholecalciferol cholesterol emulsion on renal fibrosis and aquaporin 2 and 4 in mice with unilateral ureteral obstruction." in: Biomedicine & pharmacotherapy, Vol. 102, pp. 633-638, (2018) (PubMed).
抗原

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

别名

SMAD2

背景

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.,JV18,JV18-1,MADH2,MADR2,hMAD-2,hSMAD2,Smad2,SMAD2,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,Cardiovascular,Angiogenesis,SMADs,SMAD2

分子量

48 kDa/52 kDa

基因ID

4087

UniProt

Q15796

途径

Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus