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SMAD2 抗体 (pSer423, pSer425, pSer465, pSer467)

Name: SMAD2 抗体 (pSer423, pSer425, pSer465, pSer467)
Brand: antibodies-online
SKU: ABIN7265256
Availability: OutOfStock

SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of HeLa cells using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:1000.

Immunofluorescence analysis of U2OS cells using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:100.

Immunohistochemistry of paraffin-embedded Rat brain using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

Immunohistochemistry of paraffin-embedded Human esophagus using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:100 (40x lens).

IHC (p)

Immunohistochemistry of paraffin-embedded Mouse kidney using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:100 40x lens).

IHC (p)

Immunofluorescence analysis of L929 cells using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:100.

Immunofluorescence analysis of PC-12 cells using Phospho-Smad2(S465/467)/Smad3(S423/425) Polyclonal Antibody at dilution of 1:100.

7 images

产品编号 ABIN7265256

发货至: 中国

Datasheet as PDF

抗原 See all SMAD2 抗体

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
抗原表位
47

36

30

26

20

16

9

9

7

7

7

6

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer423, pSer425, pSer465, pSer467
适用
235

149

116

12

12

9

9

8

7

7

7

6

5

4

3

3

1

1
人, 小鼠, 大鼠
宿主
238

10
兔
Compatible Secondaries
克隆类型
212

36
多克隆
标记
126

18

12

10

8

8

8

8

8

7

7

5

5

5

5

5

3
This SMAD2 antibody is un-conjugated
应用范围
210

101

64

53

52

43

41

38

18

14

10

10

5

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

产品特性

Phosphorylated antibody

纯化方法

Affinity purification

免疫原

A synthetic phosphorylated peptide around S465 & S467 of human Smad2 (NP_005892.1).

亚型

IgG

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SMAD2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G9 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) antibody
SMAD2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G7 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 2-467) antibody
SMAD2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) antibody
KO Validated SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (C-Term) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (AA 181-280) antibody
SMAD2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pSer467) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) antibody
KO Validated SMAD2 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (pThr183), (pThr221) antibody
SMAD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-SMAD, Mothers Against DPP Homolog 2 (SMAD2) (N-Term) antibody
SMAD2 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

别名

Smad2 (SMAD2 产品)

别名

JV18 antibody, JV18-1 antibody, MADH2 antibody, MADR2 antibody, hMAD-2 antibody, hSMAD2 antibody, jv18 antibody, Xmad2 antibody, madh2 antibody, madr2 antibody, XSmad2 antibody, hmad-2 antibody, hsmad2 antibody, jv18-1 antibody, smad-2 antibody, fj43c06 antibody, wu:fj43c06 antibody, 7120426M23Rik antibody, Madh2 antibody, Madr2 antibody, Smad-2 antibody, mMad2 antibody, MAD homolog 2 antibody, Mothers against DPP homolog 2 antibody, SMAD 2 antibody, Smad2 antibody, SMAD family member 2 antibody, SMAD family member 2-Z antibody, SMAD family member 2 S homeolog antibody, SMAD2 antibody, SMAD2Z antibody, smad2 antibody, smad2.S antibody, Smad2 antibody

背景

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin.

分子量

Observed_MW: 52 kDa/60 kDa
Calculated_MW: 48 kDa/52 kDa/25 kDa/35 kDa/43 kDa

基因ID

4087, 4088

UniProt

Q15796, P84022

途径

Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus