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RPRD1B 抗体

RPRD1B 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6147185
发货至: 中国
  • 抗原 See all RPRD1B 抗体
    RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
    适用
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    宿主
    • 42
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    克隆类型
    • 42
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    多克隆
    标记
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    This RPRD1B antibody is un-conjugated
    应用范围
    • 41
    • 18
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    • 5
    • 2
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    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant protein of human rprd1b
    亚型
    IgG
    Top Product
    Discover our top product RPRD1B Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RPRD1B (Regulation of Nuclear Pre-mRNA Domain Containing 1B (RPRD1B))
    别名
    rprd1b (RPRD1B 产品)
    别名
    fb23h08 antibody, zgc:55687 antibody, wu:fb23h08 antibody, rprd1ba antibody, MGC130705 antibody, C13H20ORF77 antibody, C20orf77 antibody, CREPT antibody, NET60 antibody, dJ1057B20.2 antibody, 2610304G08Rik antibody, 2810446G03Rik antibody, Crept antibody, RGD1304782 antibody, regulation of nuclear pre-mRNA domain containing 1B antibody, regulation of nuclear pre-mRNA domain containing 1B L homeolog antibody, rprd1b antibody, rprd1b.L antibody, RPRD1B antibody, Rprd1b antibody
    背景
    Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.,RPRD1B,C20orf77,CREPT,NET60,dJ1057B20.2,K-H,Kub5-Hera,rprd1b,rprd1b
    分子量
    36 kDa
    基因ID
    58490
    UniProt
    Q9NQG5
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