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NF-kB p65 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects NF-kB p65 in WB, IP 和 IF. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN6146862
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NF-kB p65 抗体 (C-Term) (ABIN6146862)

抗原

See all NF-kB p65 (NFkBP65) 抗体
NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

适用

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宿主

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克隆类型

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多克隆

标记

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This NF-kB p65 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
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    C-Term

    序列

    VSALAQAPAP VPVLAPGPPQ AVAPPAPKPT QAGEGTLSEA LLQLQFDDED LGALLGNSTD PAVFTDLASV DNSEFQQLLN QGIPVAPHTT EPMLMEYPEA ITRLVTGAQR PPDPAPAPLG APGLPNGLLS GDEDFSSIAD MDFSALLSQI SS

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human NF-kB p65/RelA (NP_068810.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).

    Liu, Wang, Qiu, Song, Wang, Liu: "Adipocytes promote nicotine-induced injury of endothelial cells via the NF-κB pathway." in: Experimental cell research, Vol. 359, Issue 1, pp. 251-256, (2017) (PubMed).

    Li, Yu, Wang, Xu, Chi, Qin, Liu: "The ω-carboxyl group of 7-ketocholesteryl-9-carboxynonanoate mediates the binding of oxLDL to CD36 receptor and enhances caveolin-1 expression in macrophages." in: The international journal of biochemistry & cell biology, Vol. 90, pp. 121-135, (2017) (PubMed).

  • 抗原

    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

    别名

    RELA

    背景

    NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.,NFKB3,p65,NF-kB p65,RELA,CMCU,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,RELA

    分子量

    58 kDa/59 kDa/60 kDa

    基因ID

    5970

    UniProt

    Q04206

    途径

    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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