PSTPIP1 抗体 (AA 157-416)
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- 抗原 See all PSTPIP1 抗体
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
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抗原表位
- AA 157-416
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSTPIP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- AFERISANGH QKQVEKSQNK ARQCKDSATE AERVYRQSIA QLEKVRAEWE QEHRTTCEAF QLQEFDRLTI LRNALWVHSN QLSMQCVKDD ELYEEVRLTL EGCSIDADID SFIQAKSTGT EPPAPVPYQN YYDREVTPLT SSPGIQPSCG MIKRFSGLLH GSPKTTSLAA SAASTETLTP TPERNEGVYT AIAVQEIQGN PASPAQEYRA LYDYTAQNPD ELDLSAGDIL EVILEGEDGW WTVERNGQRG FVPGSYLEKL
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 157-416 of human PSTPIP1 (NP_003969.2).
- 亚型
- IgG
- Top Product
- Discover our top product PSTPIP1 Primary Antibody
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anti-Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 1-416) antibody
PSTPIP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D5 unconjugated
anti-Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 157-416) antibodyPSTPIP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 157-416) antibodyPSTPIP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (AA 89-118), (N-Term) antibodyPSTPIP1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB31127 unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- 别名
- PSTPIP1 (PSTPIP1 产品)
- 别名
- cd2bp1 antibody, cd2bp1l antibody, cd2bp1s antibody, h-pip antibody, papas antibody, pstpip antibody, PSTPIP1 antibody, CD2BP1 antibody, CD2BP1L antibody, CD2BP1S antibody, H-PIP antibody, PAPAS antibody, PSTPIP antibody, def-2 antibody, proline-serine-threonine phosphatase interacting protein 1 antibody, proline-serine-threonine phosphatase interacting protein 1 S homeolog antibody, proline-serine-threonine phosphatase-interacting protein 1 antibody, PSTPIP1 antibody, pstpip1.S antibody, pstpip1 antibody, Pstpip1 antibody
- 背景
- This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response.,PSTPIP1,CD2BP1,CD2BP1L,CD2BP1S,H-PIP,PAPAS,PSTPIP,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,PSTPIP1
- 分子量
- 45 kDa/47 kDa
- 基因ID
- 9051
- UniProt
- O43586
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