PSME4 抗体 (AA 1634-1843)
This anti-PSME4 antibody is a 兔 多克隆 antibody detecting PSME4 in WB 和 IHC. Suitable for 人.
Quick Overview for PSME4 抗体 (AA 1634-1843) (ABIN6146359)
抗原
See all PSME4 抗体
PSME4
(Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
适用
人
宿主
兔
克隆类型
多克隆
标记
This PSME4 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
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抗原表位
- AA 1634-1843
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序列
- LYPHQVPLVL QVLKQTARSS SWHARYTVLT YLQTMVFYNL FIFLNNEDAV KDIRWLVISL LEDEQLEVRE MAATTLSGLL QCNFLTMDSP MQIHFEQLCK TKLPKKRKRD PGSVGDTIPS AELVKRHAGV LGLGACVLSS PYDVPTWMPQ LLMNLSAHLN DPQPIEMTVK KTLSNFRRTH HDNWQEHKQQ FTDDQLLVLT DLLVSPCYYA
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1634-1843 of human PSME4 (NP_055429.2).
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亚型
- IgG
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anti-Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4) (AA 105-198) antibody
PSME4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4) (AA 503-535) antibodyPSME4 适用: 人 WB 宿主: 兔 Polyclonal RB55279 unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PSME4 (Proteasome (Prosome, Macropain) Activator Subunit 4 (PSME4))
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别名
- PSME4
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背景
- Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.,PSME4,PA200,Cell Biology & Developmental Biology,Ubiquitin,PSME4
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分子量
- 24 kDa/113 kDa/139 kDa/211 kDa
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基因ID
- 23198
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UniProt
- Q14997
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途径
- DNA Replication, Synthesis of DNA
抗原
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