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PRKAB2 抗体 (AA 1-272)

PRKAB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6146179
发货至: 中国
  • 抗原 See all PRKAB2 抗体
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    抗原表位
    • 14
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-272
    适用
    • 41
    • 21
    • 11
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 10
    • 1
    克隆类型
    • 34
    • 7
    多克隆
    标记
    • 30
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PRKAB2 antibody is un-conjugated
    应用范围
    • 36
    • 24
    • 20
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MGNTTSDRVS GERHGAKAAR SEGAGGHAPG KEHKIMVGST DDPSVFSLPD SKLPGDKEFV SWQQDLEDSV KPTQQARPTV IRWSEGGKEV FISGSFNNWS TKIPLIKSHN DFVAILDLPE GEHQYKFFVD GQWVHDPSEP VVTSQLGTIN NLIHVKKSDF EVFDALKLDS MESSETSCRD LSSSPPGPYG QEMYAFRSEE RFKSPPILPP HLLQVILNKD TNISCDPALL PEPNHVMLNH LYALSIKDSV MVLSATHRYK KKYVTTLLYK PI
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-272 of human PRKAB2 (NP_005390.1).
    亚型
    IgG
    Top Product
    Discover our top product PRKAB2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    别名
    PRKAB2 (PRKAB2 产品)
    别名
    prkab2 antibody, MGC64365 antibody, PRKAB2 antibody, DKFZp469M1118 antibody, 5730553K21Rik antibody, AW049591 antibody, BB124140 antibody, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog antibody, protein kinase AMP-activated non-catalytic subunit beta 2 antibody, protein kinase, AMP-activated, beta 2 non-catalytic subunit antibody, prkab2.L antibody, PRKAB2 antibody, prkab2 antibody, Prkab2 antibody
    背景
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.,PRKAB2,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Warburg Effect,Cardiovascular,Lipids,Fatty Acids,Regulators,PRKAB2
    分子量
    21 kDa/30 kDa
    基因ID
    5565
    UniProt
    O43741
    途径
    AMPK Signaling, Warburg Effect
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