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PPP2R2B 抗体 (AA 160-260)

PPP2R2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6146087
发货至: 中国
  • 抗原 See all PPP2R2B 抗体
    PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-260
    适用
    • 54
    • 27
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 50
    • 5
    克隆类型
    • 50
    • 5
    多克隆
    标记
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP2R2B antibody is un-conjugated
    应用范围
    • 41
    • 24
    • 13
    • 13
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    KIRWLPQQNA AYFLLSTNDK TVKLWKVSER DKRPEGYNLK DEEGRLRDPA TITTLRVPVL RPMDLMVEAT PRRVFANAHT YHINSISVNS DYETYMSADD L
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human PP2A-B55beta/PR55beta/PP2A-B55beta/PR55beta/PPP2R2B (NP_858060.2).
    亚型
    IgG
    Top Product
    Discover our top product PPP2R2B Primary Antibody
  • 应用备注
    WB,1:1000 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))
    别名
    PPP2R2B (PPP2R2B 产品)
    别名
    B55BETA antibody, PP2AB55BETA antibody, PP2ABBETA antibody, PP2APR55B antibody, PP2APR55BETA antibody, PR2AB55BETA antibody, PR2ABBETA antibody, PR2APR55BETA antibody, PR52B antibody, PR55-BETA antibody, PR55BETA antibody, SCA12 antibody, Pppr2b2 antibody, 2900026H06Rik antibody, 6330404L05Rik antibody, E130009M08Rik antibody, PP2A-PR55B antibody, PP2A antibody, ppp2r2b-a antibody, ppp2r2c antibody, ppp2r2b antibody, zgc:101861 antibody, PPP2R2B antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, protein phosphatase 2, regulatory subunit B, beta antibody, protein phosphatase 2 regulatory subunit B, beta L homeolog antibody, protein phosphatase 2 regulatory subunit B, beta antibody, protein phosphatase 2, regulatory subunit B, beta b antibody, PPP2R2B antibody, Ppp2r2b antibody, ppp2r2b.L antibody, ppp2r2b antibody, ppp2r2bb antibody
    背景
    The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12.,PPP2R2B,B55BETA,PP2AB55BETA,PP2ABBETA,PP2APR55B,PP2APR55BETA,PR2AB55BETA,PR2ABBETA,PR2APR55BETA,PR52B,PR55-BETA,PR55BETA,SCA12,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Wnt/β-Catenin Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PPP2R2B
    分子量
    50 kDa/51 kDa/52 kDa/58 kDa/62 kDa
    基因ID
    5521
    UniProt
    Q00005
    途径
    PI3K-Akt Signaling, Mitotic G1-G1/S Phases, Hepatitis C
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