×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
Pellino 1 抗体 (AA 1-250)
PELI1
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
Pellino 1抗体详情
(hide)
抗原
See all Pellino 1 (PELI1) 抗体
Pellino 1 (PELI1)
(Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
抗原表位
All epitopes for Pellino 1 抗体
AA 1-250
适用
All reactivities for Pellino 1 抗体
人
宿主
All hosts for Pellino 1 抗体
兔
克隆类型
All clonalities for Pellino 1 抗体
多克隆
标记
All conjugates for Pellino 1 抗体
This Pellino 1 antibody is un-conjugated
应用范围
All applications for Pellino 1 抗体
Western Blotting (WB)
序列
MFSPDQENHP SKAPVKYGEL IVLGYNGSLP NGDRGRRKSR FALFKRPKAN GVKPSTVHIA CTPQAAKAIS NKDQHSISYT LSRAQTVVVE YTHDSNTDMF QIGRSTESPI DFVVTDTVPG SQSNSDTQSV QSTISRFACR IICERNPPFT ARIYAAGFDS SKNIFLGEKA AKWKTSDGQM DGLTTNGVLV MHPRNGFTED SKPGIWREIS VCGNVFSLRE TRSAQQRGKM VEIETNQLQD GSLIDLCGAT
交叉反应
大鼠
产品特性
Polyclonal Antibodies
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PELI1 (NP_065702.2).
亚型
IgG
Top Product
Discover our top product PELI1 Primary Antibody
Alternatives
(show)
anti-Pellino E3 Ubiquitin Protein Ligase 1 (PELI1) (AA 107-156) antibody
PELI1
适用: 人, 小鼠, 大鼠, Cow, 马, 斑马鱼, 犬, 兔, 豚鼠, Hamster, 非洲爪蟾, Bat, 猴, 小鸡, Pig
WB
宿主: 兔
Polyclonal
unconjugated
使用细节
(hide)
应用备注
WB,1:500 - 1:2000
限制
仅限研究用
贮存及处理
(hide)
状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
Pellino 1目标详情
(hide)
抗原
Pellino 1 (PELI1)
(Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))
别名
PELI1 (PELI1 产品 )
别名
2810468L03Rik antibody, A930031K15Rik antibody, AA409794 antibody, AI586297 antibody, D11Ertd676e antibody, peli1 antibody, peli1.L antibody, pellino1 antibody, xpellino1 antibody, wu:fd12d01 antibody, zgc:153297 antibody, pellino E3 ubiquitin protein ligase 1 antibody, pellino 1 antibody, pellino E3 ubiquitin protein ligase 1 S homeolog antibody, pellino E3 ubiquitin protein ligase 1b antibody, PELI1 antibody, Peli1 antibody, peli1.S antibody, peli1b antibody
背景
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation. Mediates 'Lys-48'-linked polyubiquitination of RIPK3 leading to its subsequent proteasome-dependent degradation, preferentially recognizes and mediates the degradation of the 'Thr-182' phosphorylated form of RIPK3. Negatively regulates necroptosis by reducing RIPK3 expression. Mediates 'Lys-63'-linked ubiquitination of RIPK1.,PELI1,Signal Transduction,Kinase,Immunology & Inflammation,NF-kB Signaling Pathway,PELI1
分子量
46 kDa
基因ID
57162
UniProt
Q96FA3
途径
Activation of Innate immune Response , Toll-Like Receptors Cascades
Recently viewed
(hide)