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PCSK1 抗体 (AA 604-753)

PCSK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145322
发货至: 中国
  • 抗原 See all PCSK1 抗体
    PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
    抗原表位
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 604-753
    适用
    • 18
    • 15
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 19
    • 6
    克隆类型
    • 19
    • 6
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    This PCSK1 antibody is un-conjugated
    应用范围
    • 16
    • 14
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    PRVYTSYNTV QNDRRGVEKM VDPGEEQPTQ ENPKENTLVS KSPSSSSVGG RRDELEEGAP SQAMLRLLQS AFSKNSPPKQ SPKKSPSAKL NIPYENFYEA LEKLNKPSQL KDSEDSLYND YVDVFYNTKP YKHRDDRLLQ ALVDILNEEN
    交叉反应
    小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 604-753 of human PCSK1 (NP_000430.3).
    亚型
    IgG
    Top Product
    Discover our top product PCSK1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))
    别名
    PCSK1 (PCSK1 产品)
    别名
    BMIQ12 antibody, NEC1 antibody, PC1 antibody, PC3 antibody, SPC3 antibody, Nec-1 antibody, Nec1 antibody, Phpp-1 antibody, BDP antibody, PC1/3 antibody, proprotein convertase subtilisin/kexin type 1 antibody, prohormone convertase 1 antibody, PCSK1 antibody, Pcsk1 antibody, pcsk1 antibody, PC1B antibody
    背景
    This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene,PCSK1,BMIQ12,NEC1,PC1,PC3,SPC3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Ubiquitin,Endocrine & Metabolism,Neuroscience,PCSK1
    分子量
    79 kDa/84 kDa
    基因ID
    5122
    UniProt
    P29120
    途径
    Peptide Hormone Metabolism
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