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PARP1 抗体 (AA 81-390)

Name: PARP1 抗体 (AA 81-390)
Brand: antibodies-online
SKU: ABIN6145232
Availability: OutOfStock

This anti-PARP1 antibody is a 兔多克隆 antibody detecting PARP1 in WB, IHC, IP 和 IF. Suitable for 人. This Primary Antibody has been cited in 2+ publications.

Apoptosis related proteins were detected in EOMA cells after treated with DHTS and propranolol. (PARP1 抗体 (AA 81-390))

Immunohistochemistry of paraffin-embedded human tonsil using PARP1 antibody. (PARP1 抗体 (AA 81-390))

IHC (p)

Immunohistochemistry of paraffin-embedded human appendix using PARP1 antibody. (PARP1 抗体 (AA 81-390))

IHC (p)

Western blot analysis of extracts of various cell lines, using PARP1 antibody. (PARP1 抗体 (AA 81-390))

Immunohistochemistry of paraffin-embedded human vermiform appendix using PARP1 Antibody. (PARP1 抗体 (AA 81-390))

IHC (p)

Immunohistochemistry of paraffin-embedded human breast cancer using PARP1 Antibody. (PARP1 抗体 (AA 81-390))

IHC (p)

Immunofluorescence analysis of U2OS cells using PARP1 antibody. (PARP1 抗体 (AA 81-390))

Immunohistochemistry of paraffin-embedded rat testis using PARP1 Antibody. (PARP1 抗体 (AA 81-390))

IHC (p)

8 images

(2 references)

产品编号 ABIN6145232

发货至: 中国

Datasheet as PDF

Quick Overview for PARP1 抗体 (AA 81-390) (ABIN6145232)

抗原

See all PARP1 抗体

PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PARP1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

抗原表位
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8

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AA 81-390

序列

DQQKVKKTAE AGGVTGKGQD GIGSKAEKTL GDFAAEYAKS NRSTCKGCME KIEKGQVRLS KKMVDPEKPQ LGMIDRWYHP GCFVKNREEL GFRPEYSASQ LKGFSLLATE DKEALKKQLP GVKSEGKRKG DEVDGVDEVA KKKSKKEKDK DSKLEKALKA QNDLIWNIKD ELKKVCSTND LKELLIFNKQ QVPSGESAIL DRVADGMVFG ALLPCEECSG QLVFKSDAYY CTGDVTAWTK CMVKTQTPNR KEWVTPKEFR EISYLKKLKV KKQDRIFPPE TSASVAATPP PSTASAPAAV NSSASADKPL

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2).

亚型

IgG
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
KO Validated PARP1 适用: 人 WB, IP, IF, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibody
PARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibody
PARP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibody
PARP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibody
PARP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
PARP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibody
PARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term) antibody
PARP1 适用: 人 WB, IHC, 2D-PAGE 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibody
PARP1 适用: 人 WB, 2D-PAGE 宿主: 兔 Polyclonal unconjugated

anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 183-214) antibody
PARP1 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:1000 - 1:3000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Huang, Cui, Chen, Yang, Lian, Liu, Su, Liu, Wang, Hu, Ouyang, Li, Lu: "NVP-BEZ235 synergizes cisplatin sensitivity in osteosarcoma." in: Oncotarget, Vol. 9, Issue 12, pp. 10483-10496, (2018) (PubMed).

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
抗原

PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

别名

PARP1

背景

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.,ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,PARP1,Cleaved PARP,PARP1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,other,DNA Damage & Repair,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,PARP1

分子量

113 kDa

基因ID

142

UniProt

P09874

途径

Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location