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TNF alpha 抗体
TNF alpha
适用: 人
WB, Func, EIA
宿主: 小鼠
Monoclonal
MAb1
unconjugated
TNF alpha抗体详情
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抗原
See all TNF alpha 抗体
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
适用
All reactivities for TNF alpha 抗体
人
宿主
All hosts for TNF alpha 抗体
小鼠
克隆类型
All clonalities for TNF alpha 抗体
单克隆
标记
All conjugates for TNF alpha 抗体
This TNF alpha antibody is un-conjugated
应用范围
All applications for TNF alpha 抗体
Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
特异性
This antibody recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
纯化方法
Affinity Chromatography
免疫原
Human TNF
克隆位点
MAb1
亚型
IgG1
Top Product
Discover our top product TNF alpha Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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缓冲液
PBS, pH 7.4, 0.09 % Sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
Store the antibody undiluted at 2-8 °C.
TNF alpha目标详情
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抗原
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
别名
Tumor Necrosis Factor (TNF-Alpha) (TNF alpha 产品 )
别名
DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
背景
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
基因ID
7124
NCBI登录号
NP_000585
UniProt
P01375
途径
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , TLR signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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