TNF alpha 抗体
Our Local Distributor
北京 101111
Quick Overview for TNF alpha 抗体 (ABIN614424)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
-
纯化方法
- Affinity Chromatography
-
免疫原
- Human TNF
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS, pH 7.4, 0.09 % Sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
-
别名
- Tumor Necrosis Factor (TNF-Alpha)
-
背景
- TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
-
基因ID
- 7124
-
NCBI登录号
- NP_000585
-
UniProt
- P01375
-
途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
-