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MCFD2 抗体 (AA 27-146)

MCFD2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6143636
发货至: 中国
  • 抗原 See all MCFD2 抗体
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    抗原表位
    • 15
    • 7
    • 2
    • 1
    AA 27-146
    适用
    • 25
    • 23
    • 22
    宿主
    • 29
    • 11
    克隆类型
    • 30
    • 10
    多克隆
    标记
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCFD2 antibody is un-conjugated
    应用范围
    • 27
    • 15
    • 13
    • 13
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    EEPAASFSQP GSMGLDKNTV HDQEHIMEHL EGVINKPEAE MSPQELQLHY FKMHDYDGNN LLDGLELSTA ITHVHKEEGS EQAPLMSEDE LINIIDGVLR DDDKNNDGYI DYAEFAKSLQ
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 27-146 of human MCFD2 (NP_644808.1).
    亚型
    IgG
    Top Product
    Discover our top product MCFD2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))
    别名
    MCFD2 (MCFD2 产品)
    别名
    hm:zeh1186 antibody, wu:fc23b10 antibody, wu:fd50d08 antibody, zgc:103713 antibody, zgc:109915 antibody, MCFD2 antibody, DKFZp469B098 antibody, F5F8D antibody, F5F8D2 antibody, LMAN1IP antibody, SDNSF antibody, 1810021C21Rik antibody, F5f8d antibody, Lman1ip antibody, Sdnsf antibody, multiple coagulation factor deficiency 2 antibody, multiple coagulation factor deficiency 2 L homeolog antibody, MCFD2 antibody, mcfd2 antibody, mcfd2.L antibody, Mcfd2 antibody
    背景
    This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,MCFD2,F5F8D,F5F8D2,LMAN1IP,SDNSF,Signal Transduction,MCFD2
    分子量
    10 kDa/14 kDa/16 kDa
    基因ID
    90411
    UniProt
    Q8NI22
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